Levels of Circulating Progenitor Cells, Cardiovascular Outcomes and Death
نویسندگان
چکیده
Prediction of future cardiovascular events (CVEs) and death by combinations of traditional risk factors yields inaccurate risk estimates, despite advancements in statistical methods and modeling. As a significant proportion of CVE occurs in subjects stratified into low-intermediate risk categories, the sake for cardiovascular risk biomarkers has attracted great interest. An ideal cardiovascular risk biomarker should be biologically related to disease pathophysiology, easily measurable, associated with prevalent and incident cardiovascular disease (CVD) in different populations, able to improve risk stratification, routinely available in clinical practice, and able to drive clinical decisions.
منابع مشابه
Levels of Circulating Progenitor Cells, Cardiovascular Outcomes and Death: A Meta-Analysis of Prospective Observational Studies.
RATIONALE Circulating progenitor cells (CPCs), including endothelial progenitor cells (EPCs) are biologically related to many aspects of cardiovascular disease, as they promote angiogenesis and vascular repair. OBJECTIVE We herein aimed to meta-analyze studies reporting the prognostic role of the CPC/EPC measure on cardiovascular outcomes and death. METHODS AND RESULTS We screened the Engli...
متن کاملTelomere Shortening, Regenerative Capacity, and Cardiovascular Outcomes.
RATIONALE Leukocyte telomere length (LTL) is a biological marker of aging, and shorter LTL is associated with adverse cardiovascular outcomes. Reduced regenerative capacity has been proposed as a mechanism. Bone marrow-derived circulating progenitor cells are involved in tissue repair and regeneration. OBJECTIVE Main objective of this study was to examine the relationship between LTL and prog...
متن کاملEffect of two different intensity of physical activity on circulating endothelial progenitor cells (EPC) in healthy young women
The purpose of this study was to determine the effect of two different intensities of physical activity on circulating endothelial progenitor cells (EPC) in healthy young women. For this purpose, 15 female students from volunteers were randomly selected via questionnaire (group 1: mean age 22 ±1/8 years, BMI 20/81±1/91 kg/m2, n = 8. group 2: mean age 21 ±1/5 years, BMI 20/38 ± 1/66 kg/m2, ...
متن کاملEffect of Scurrula atropurpurea on nitric oxide, endothelial damage, and endothelial progenitor cells of DOCA-salt hypertensive rats
Objective(s):To know whether Scurrula atropurpurea is able to modulate total plasma nitrate/nitrite levels, decrease endothelial damage, and increase endothelial progenitor cells (EPCs) in hypertensive rats. Materials and Methods: The rats were divided in 5 groups: control (normotensive) group, Desoxy cortico sterone (DOCA)-salt hypertensive group, and three DOCA-salt hypertensive groups. All 5...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2016